Little Yue's mother fell ill and was hospitalized. Her father took her and her four-year-old sister Xiao Mei to live in the countryside. They found the environment there to be very intriguing and discovered many interesting things. They encountered numerous little spirits who guided them into their own environment, witnessing many strange phenomena in their world. Moreover, they became friends with a chubby and adorable Totoro.

In the year 2805 AD, human civilization had reached a high level of development. However, due to pollution and a significant increase in household waste, Earth became unsuitable for human habitation. In the face of this crisis, humans were forced to leave their homeland and embark on a long and boundless journey through space. Before departure, they entrusted the company Buynlarge with the task of cleaning up Earth's waste. The company developed robots called WALL·E (Waste Allocation Load Lifters – Earth) to undertake this heavy responsibility.